Why Choose Royal CynarArt®
Nature's Excellence, Delivered with Integrity
Royal CynarArt®-Mediterranean Premium Source
Grown under Mediterranean sunshine, our artichokes, certified with Protected Designation of Origin (PDO) from France, accumulate rich polyphenols and flavonoids through seasonal cycles. Their unique environment and traditional cultivation methods yield high levels of cynarin, delivering potent liver-cleansing and digestive benefits. France’s stringent agricultural standards and PDO certification ensure the purity and efficacy of each artichoke, providing natural vitality for beauty and liver health.
Royal CynarArt®-Rich in artichoke acid
HPLC analysis comparing our Royal CynarArt® with Chinses artichoke extract reveals that our sample is rich in dicaffeoylquinic acids, including cynarin (1,3-dicaffeoylquinic acid) and 1,5-dicaffeoylquinic acid, with a diverse range of polyphenols and a complex chromatogram, indicating higher functional activity. In contrast, standard artichoke extract lacks cynarin peaks, primarily containing monocaffeoylquinic acids with simpler components. Cultivated under Mediterranean sunshine with seasonal cycles, our artichokes accumulate abundant polyphenols and flavonoids. This unique environment and traditional cultivation methods yield high cynarin levels, delivering significant liver-cleansing and digestive benefits.
Royal CynarArt®-liver protection function
Artichoke extract demonstrates significant hepatoprotective effects through multiple mechanisms. Studies show it effectively reduces plasma ALT, AST, and ALP enzyme activities in carbon tetrachloride (CCl4)-induced liver injury rats, mitigating hepatocyte membrane damage and promoting tissue repair. Additionally, it markedly enhances superoxide dismutase (SOD) activity and glutathione (GSH) levels, bolstering antioxidant defense, and suppresses lipid peroxidation products (TBARS), alleviating oxidative stress on the liver. Its hepatoprotective mechanisms are primarily attributed to polyphenol compounds (e.g., chlorogenic acid), which provide antioxidant benefits by neutralizing free radicals, regulating liver enzyme activity, and maintaining cell membrane stability for comprehensive protection. Experiments confirm that a 1.5 g/kg dose of artichoke extract offers optimal efficacy and good safety, providing a strong basis for developing natural liver-protective agents.
Pic 1 and Pic 2 show：
The results show that ALT and AST activities in the CCl group (Negative Control) were significantly higher than in the Control group, while activities in the pretreatment group (I–II) and regeneration groups (IV–VI) were significantly reduced. Artichoke extract significantly lowered plasma ALT and AST activities in CCl-induced liver injury rats, indicating its role in reducing hepatocyte membrane damage and promoting liver repair.
Pic 3 and Pic 4 show：
The results show that GSH levels in the CCl group were reduced, while the high-dose pretreatment group (I) restored GSH levels to those of the control group. Artichoke extract pretreatment (1.5 g/kg) significantly restored plasma glutathione (GSH) levels, enhancing the antioxidant defense capacity of hepatocytes.
Pic 5 and Pic 6 show：
The results show that SOD activity in the CCl group was significantly reduced, while the pretreatment group (I–II) restored SOD activity to near control group levels. Figure 7C indicates that SOD activity in liver homogenates of the regeneration groups (IV–VI) significantly increased. Artichoke extract enhances the body’s free radical scavenging capacity by increasing superoxide dismutase (SOD) activity.
Pic 7 and Pic 8 show：
The results show that TBARS levels in the CCl group were significantly elevated, while the regeneration groups (IV–VI) exhibited significantly reduced TBARS levels. Artichoke extract significantly lowers lipid peroxidation products (TBARS) in CCl-induced models, indicating its role in inhibiting oxidative damage.
Pic 9 show：
The results show that ALP activity in the CCl group was elevated, while the pretreatment group (I) exhibited significantly reduced ALP activity. Artichoke extract (1.0 g/kg) significantly lowers alkaline phosphatase (ALP) activity, improving bile secretion function.
Royal CynarArt®-Anti-Inflammatory and Antioxidant Effects
Results show that artichoke extract significantly enhances free radical scavenging capacity. In DPPH and ABTS assays, its antioxidant activity was over 10 times higher than the control group, with superior effects when combined with sourdough. In vitro cell studies revealed that metabolites of artichoke extract fermented by gut microbiota improved the viability of human keratinocytes under oxidative stress, with 42-hour fermentation products showing the most pronounced protective effects. Regarding anti-inflammatory properties, artichoke extract combined with sourdough fermentation broth significantly reduced the expression of pro-inflammatory cytokines (TNF-α and IL-1β) in Caco-2 cells, approaching normal cell levels. The study indicates that polyphenolic compounds in artichoke extract drive its antioxidant and anti-inflammatory potential, further enhanced by synergy with sourdough, providing a scientific basis for functional food development.
Pic 1 and Pic 2 show：
The fermentation product of bread containing artichoke leaf extract can enhance the viability of human keratinocytes under oxidative stress, and the effect is more obvious after 42 hours of fermentation.
Pic 3 show：
Artichoke leaf extract significantly enhances the antioxidant capacity of bread, with DPPH and ABTS values in the added group far exceeding those of the non-added group. The combination of sourdough and artichoke extract yields even superior results.
Pic 4 show：
Bread fermentation broth containing artichoke leaf extract and sourdough significantly reduces the expression of pro-inflammatory cytokines TNF-α and IL-1β, with anti-inflammatory effects approaching normal levels.
Royal CynarArt®-The Safety of Black Ginger
Internationally Recognized Safety
Germany’s Commission E has listed artichoke leaf extract as a recommended treatment for high cholesterol and liver and gallbladder support. The European Food Safety Authority (EFSA) has confirmed its safety as a dietary supplement, and the U.S. NIH database also recognizes its low toxicity. Multiple authoritative evaluations jointly validate that artichoke extract is safe and reliable when used within recommended dosages, providing strong assurance for its use in health supplementation.
Clinically Proven Safety and Tolerability
A study published in Phytomedicine showed that among 108 patients with high cholesterol, daily intake of 1,800 mg of dry artichoke leaf extract over 12 weeks resulted in only mild gastrointestinal discomfort, with no serious adverse effects. Scientific data confirm its good tolerability, providing a reliable reference for safe daily supplementation.
Scientific Guidelines for Use
Organizations such as the European Food Safety Authority (EFSA) and France’s ANSES have established clear usage guidelines: adults should limit their intake of dry artichoke leaf extract to no more than 600 mg per day. They also advise caution for individuals with bile duct obstruction, liver or gallbladder diseases, and for pregnant women. International safety recommendations help define proper usage boundaries, ensuring that the natural benefits of artichoke extract are safely and effectively realized.
6 Efficacies of Royal CynarArt®
Liver Protection and Detoxification
Artichoke extract, rich in chlorogenic acid and cynarin, promotes bile secretion, accelerates liver metabolism, stabilizes liver enzymes, and reduces inflammation. It also offers protective benefits against fatty liver, making it a natural choice for liver health support.
Cholesterol Management and Cardiovascular Support
Polyphenols in artichoke extract help lower LDL cholesterol, raise HDL cholesterol, inhibit cholesterol synthesis, and improve lipid profiles—making it beneficial for individuals with hyperlipidemia or cardiovascular risk.
Relieving Indigestion
By promoting bile secretion and enhancing fat digestion, artichoke extract helps relieve bloating and feelings of fullness, shortens gastric emptying time, and effectively improves functional dyspepsia.
Antioxidant, Anti-Inflammatory, and Anti-Aging Benefits
Flavonoids and chlorogenic acid in artichoke extract neutralize free radicals, regulate inflammatory factors, and reduce chronic disease risk, showing significant potential in anti-aging and endocrine regulation applications.
Blood Sugar Balance and Metabolic Regulation
Inulin and polyphenols in artichoke extract work synergistically to regulate glucose absorption, enhance insulin sensitivity, stabilize blood sugar, and support the management of metabolic syndrome.
Microbiome Regulation and Immune Enhancement
Inulin in artichoke extract acts as a prebiotic, nourishing beneficial gut bacteria, balancing the microbiome, strengthening the gut barrier, activating immune cells, and boosting overall immunity.
Royal CynarArt®-Industry Trend Data
Sustained Market Growth, Reaching $2.89 Billion in 2024
According to authoritative data, the artichoke extract market surged from $2.75 billion in 2023 to $2.89 billion in 2024, achieving a compound annual growth rate (CAGR) of 5.3%. This growth is driven by rising consumer demand for natural plant extracts, liver health supplements, and antioxidant nutraceuticals. With the trend toward healthy aging gaining momentum, the market is projected to exceed $3.06 billion in 2025, with the CAGR increasing to 5.7%, fueled by the expansion of the nutraceutical industry and growing demand for gut health solutions.
Europe Leads Globally, Fueled by Herbal Traditions
With a rich heritage in herbal medicine and high acceptance of natural health products, Europe dominates the artichoke extract market. Countries like Germany, Italy, and France widely incorporate it into pharmacopoeias and herbal formulations, particularly for liver health products. From daily dietary supplements to specialized pharmaceutical formulas, Europe’s focus on natural, effective products continues to lead global industry trends.
Cross-Industry Expansion and Multi-Sector Potential
Artichoke extract is breaking beyond traditional dietary supplements, making strong inroads into functional foods, plant-based beverages, and natural skincare. Its versatile, natural properties align with “pure plant” and “clean label” consumer trends, promoting liver detoxification in beverages and antioxidant, anti-inflammatory benefits in skincare. As application scenarios expand, this natural ingredient is unleashing diverse potential, becoming a rising star in the health and beauty industries.
Providing Raw Materials for Health
Contact Us
ESSENCE SOURCE USA, INC
855 Conklin street suite S,
Farmingdale NY 11735
Green Life Co. Ltd.
Pioneering Park,Hi-tech Development Zone,Xi’an, China
Phone
+086 - 029-88259472 +86-152-2931-6860